2007年VOA标准英语-Study Shows Restless Leg Syndrome Traced to Gen

It has been estimated that ten percent of people worldwide suffer from Restless Leg Syndrome¹.  RLS is a neurological disorder² that makes it difficult to sit or lie still for long periods of time.  The disorder often occurs in the evening and at night, so falling sleep or staying asleep is especially difficult for those who have it.  VOA's Melinda Smith reports on results of two studies that trace the problem back to an inherited gene³.

How many of us take for granted a good night's sleep?  If you wake up often or do not sleep well during the night, there may be a genetic⁴ reason why.

Lynn Kaiser

Dr. John Winkelman, medical director of a sleep health center in Boston, Massachusetts, describes common symptoms of those who have RLS. "Intense discomfort⁵ and need to move the legs is most pronounced at night."

Two new studies in Iceland and the United States have confirmed that the condition is more than just in one's own mind.  It is inherited through genetic variations.  How those genes⁶ influence the response in the brain is still uncertain.

Scientists also believe an iron deficiency affects the production of dopamine, a neurotransmitter in the central nervous system which controls movement and sensation.

The researchers say they believe the discovery of a genetic link will finally lead to effective treatment.  That would be good news for people like Lynn Kaiser, who just want to get some rest: "My goal is to manage it, rather than it manage me."