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VOA标准英语2015--Generic Form of Pediatric HIV Drug OK’d

时间:2015-02-27 13:59:29

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Generic1 Form of Pediatric HIV Drug OK’d

A new licensing2 agreement with the pharmaceutical3 company MERCK allows for the manufacture of a generic version of a pediatric AIDS drug. It may be two years before it’s readily available in low- and middle-income countries. However, it’s a step toward having greater access to HIV medicines specifically designed for children.

It’s estimated there are more than three million children living with HIV, but less than a third of them received antiretroviral therapy in 2013.The U.N.-backed Medicines Patent Pool estimates 700 children are newly infected each day, while 500 die of AIDS-related causes.

The MERCK drug – raltegravir – has been approved for children as young as four weeks.

Medicines Patent Pool Executive Director Greg Perry said pediatric AIDS drugs are a neglected area of health care. As a result, many kids with HIV are forced to take adult formulations of antiretroviral pills, or ARVs.

“They will taste incorrect. They will have high alcohol content. They will be too big. The children won’t take them. So, there’s a whole series of problems with using adult formulations," he said. "And finally, worst of all, of course, is that when you try and break them down they’re not really perfectly4 digestible to the children or working properly into the bloodstream.”

Perry explained what the licensing agreement with MERCK will do.

“It does allow really two things. It allows for generic companies to develop and then manufacture low cost versions of raltegravir. It also enables them to make improvements upon the product and, indeed, to use them in combination with other products," he said. "[This] is important because you want to see new fixed5 dose combinations of pediatric formulations because that’s a clear need in the pediatric field.”

Currently, the drug is considered a third line of defense6. But Perry said there are discussions about using it as a first- or second-line drug.

“It’s an important alternative to [the] current, sort of, preferred product, which is called lopinavir/ritonavir. So, from a public health point of view it’s an important product,” he said.

Perry added it’s important to have a wide variety of ARVs in the event HIV builds up resistance to current treatment. He said the Pediatric HIV Treatment Initiative aims to develop new fixed dose drug combinations. The goal is to have up to six new formulations over the next three years.

U.S. Global AIDS Coordinator7 Dr. Deborah Birx said, “Without antiretroviral therapy 50 percent of infants with HIV die by age two and 80 percent by age five.”


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1 generic mgixr     
adj.一般的,普通的,共有的
参考例句:
  • I usually buy generic clothes instead of name brands.我通常买普通的衣服,不买名牌。
  • The generic woman appears to have an extraordinary faculty for swallowing the individual.一般妇女在婚后似乎有特别突出的抑制个性的能力。
2 licensing 7352ce0b4e0665659ae6466c18decb2a     
v.批准,许可,颁发执照( license的现在分词 )
参考例句:
  • A large part of state regulation consists of occupational licensing. 大部分州的管理涉及行业的特许批准。 来自英汉非文学 - 行政法
  • That licensing procedures for projects would move faster. 这样的工程批准程序一定会加快。 来自辞典例句
3 pharmaceutical f30zR     
adj.药学的,药物的;药用的,药剂师的
参考例句:
  • She has donated money to establish a pharmaceutical laboratory.她捐款成立了一个药剂实验室。
  • We are engaged in a legal tussle with a large pharmaceutical company.我们正同一家大制药公司闹法律纠纷。
4 perfectly 8Mzxb     
adv.完美地,无可非议地,彻底地
参考例句:
  • The witnesses were each perfectly certain of what they said.证人们个个对自己所说的话十分肯定。
  • Everything that we're doing is all perfectly above board.我们做的每件事情都是光明正大的。
5 fixed JsKzzj     
adj.固定的,不变的,准备好的;(计算机)固定的
参考例句:
  • Have you two fixed on a date for the wedding yet?你们俩选定婚期了吗?
  • Once the aim is fixed,we should not change it arbitrarily.目标一旦确定,我们就不应该随意改变。
6 defense AxbxB     
n.防御,保卫;[pl.]防务工事;辩护,答辩
参考例句:
  • The accused has the right to defense.被告人有权获得辩护。
  • The war has impacted the area with military and defense workers.战争使那个地区挤满了军队和防御工程人员。
7 coordinator Gvazk6     
n.协调人
参考例句:
  • The UN Office for the Coordination of Humanitarian Affairs, headed by the Emergency Relief Coordinator, coordinates all UN emergency relief. 联合国人道主义事务协调厅在紧急救济协调员领导下,负责协调联合国的所有紧急救济工作。
  • How am I supposed to find the client-relations coordinator? 我怎么才能找到客户关系协调员的办公室?

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