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SSS 2010-05-27

时间:2010-06-11 06:16:16

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(单词翻译)

This is Scientific American's 60-Second Science, I'm Steve Mirsky. Got a minute?

A strain of mutant mice groom1 compulsively till they seriously injure themselves. The condition is considered a good animal model for OCD, and it’s similar to the human disorder2 trichotillomania, where people pull out their own hair. Now researchers have successfully treated this pathological behavior in the mice—with a bone marrow3 transplant. The work, led by Nobel Laureate Mario Capecchi, was published in the journal Cell.

The mouse condition is related to immune system cells called microglia. These cells originate in the bone marrow and wind up in the brain, where their job is to fight off infections. But a genetic4 mutation5 leads to defective6 microglia, which drive the mice to perform the odd, self-mutilating behavior.

The researchers gave 10 mutant mice bone marrow from healthy mice. And the presence of normal microglia stopped the compulsion. It’s compelling evidence for the long-proposed link between the immune system and certain psychiatric disorders7.

Capecchi warns that bone marrow transplants are too risky8 to be commonly used against, for example, OCD. Rather, a fuller understanding of the immune system-mental illness connection should produce new treatments.

Thanks for the minute for Scientific American’s 60-Second Science. I’m Steve Mirsky.
 


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1 groom 0fHxW     
vt.给(马、狗等)梳毛,照料,使...整洁
参考例句:
  • His father was a groom.他父亲曾是个马夫。
  • George was already being groomed for the top job.为承担这份高级工作,乔治已在接受专门的培训。
2 disorder Et1x4     
n.紊乱,混乱;骚动,骚乱;疾病,失调
参考例句:
  • When returning back,he discovered the room to be in disorder.回家后,他发现屋子里乱七八糟。
  • It contained a vast number of letters in great disorder.里面七零八落地装着许多信件。
3 marrow M2myE     
n.骨髓;精华;活力
参考例句:
  • It was so cold that he felt frozen to the marrow. 天气太冷了,他感到寒冷刺骨。
  • He was tired to the marrow of his bones.他真是累得筋疲力尽了。
4 genetic PgIxp     
adj.遗传的,遗传学的
参考例句:
  • It's very difficult to treat genetic diseases.遗传性疾病治疗起来很困难。
  • Each daughter cell can receive a full complement of the genetic information.每个子细胞可以收到遗传信息的一个完全补偿物。
5 mutation t1PyM     
n.变化,变异,转变
参考例句:
  • People who have this mutation need less sleep than others.有这种突变的人需要的睡眠比其他人少。
  • So far the discussion has centered entirely around mutation in the strict sense.到目前为止,严格来讲,讨论完全集中于围绕突变问题上。
6 defective qnLzZ     
adj.有毛病的,有问题的,有瑕疵的
参考例句:
  • The firm had received bad publicity over a defective product. 该公司因为一件次品而受到媒体攻击。
  • If the goods prove defective, the customer has the right to compensation. 如果货品证明有缺陷, 顾客有权索赔。
7 disorders 6e49dcafe3638183c823d3aa5b12b010     
n.混乱( disorder的名词复数 );凌乱;骚乱;(身心、机能)失调
参考例句:
  • Reports of anorexia and other eating disorders are on the increase. 据报告,厌食症和其他饮食方面的功能紊乱发生率正在不断增长。 来自《简明英汉词典》
  • The announcement led to violent civil disorders. 这项宣布引起剧烈的骚乱。 来自《简明英汉词典》
8 risky IXVxe     
adj.有风险的,冒险的
参考例句:
  • It may be risky but we will chance it anyhow.这可能有危险,但我们无论如何要冒一冒险。
  • He is well aware how risky this investment is.他心里对这项投资的风险十分清楚。

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