(单词翻译:单击)
Worldwide, there are more than 1.5 billion overweight adults, including 400 million who are obese1. In Australia, it is estimated more than 50 per cent of women and 60 per cent of men are either overweight or obese. Although restriction2 of diet often results in initial weight loss, more than 80 per cent of obese dieters fail to maintain their reduced weight. Obese people may regain3 weight after dieting due to hormonal4 changes, a new study has shown.
The study involved 50 overweight or obese adults, with a BMI of between 27 and 40, and an average weight of 95kg, who enrolled5 in a 10-week weight loss program using a very low energy diet. Levels of appetite-regulating hormones7 were measured at baseline, at the end of the program and one year after initial weight loss.
Results showed that following initial weight loss of about 13 kgs, the levels of hormones that influence hunger changed in a way which would be expected to increase appetite. These changes were sustained for at least one year. Participants regained8 around 5kgs during the one-year period of study.
Professor Joseph Proietto from the University of Melbourne and Austin Health said the study revealed the important roles that hormones play in regulating body weight, making dietary and behavioral change less likely to work in the long-term.
"Our study has provided clues as to why obese people who have lost weight often relapse(复发) . The relapse has a strong physiological9 basis and is not simply the result of the voluntary resumption of old habits," he said.
Dr Proietto said although health promotion10 campaigns recommended obese people adopt lifestyle changes such as to be more active, they were unlikely to lead to reversal(逆转,撤销) of the obesity11 epidemic12.
"Ultimately it would be more effective to focus public health efforts in preventing children from becoming obese."
"The study also suggests that hunger following weight loss needs to be addressed. This may be possible with long-term pharmacotherapy(药物疗法) or hormone6 manipulation but these options need to be investigated," he said.
The study was done in collaboration13 with La Trobe University. It was published in the New England Journal of Medicine.
1 obese | |
adj.过度肥胖的,肥大的 | |
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2 restriction | |
n.限制,约束 | |
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3 regain | |
vt.重新获得,收复,恢复 | |
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4 hormonal | |
adj.激素的 | |
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5 enrolled | |
adj.入学登记了的v.[亦作enrol]( enroll的过去式和过去分词 );登记,招收,使入伍(或入会、入学等),参加,成为成员;记入名册;卷起,包起 | |
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6 hormone | |
n.荷尔蒙,激素,内分泌 | |
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7 hormones | |
n. 荷尔蒙,激素 名词hormone的复数形式 | |
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8 regained | |
复得( regain的过去式和过去分词 ); 赢回; 重回; 复至某地 | |
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9 physiological | |
adj.生理学的,生理学上的 | |
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10 promotion | |
n.提升,晋级;促销,宣传 | |
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11 obesity | |
n.肥胖,肥大 | |
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12 epidemic | |
n.流行病;盛行;adj.流行性的,流传极广的 | |
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13 collaboration | |
n.合作,协作;勾结 | |
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