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SSS 2012-07-13

时间:2012-09-18 08:38:58

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 Vaccines2 are desperately3 needed in the developing world. Even when they’re available and inexpensive, there’s still a major problem: most vaccines need to be refrigerated. Reaching the relevant populations often means traveling to areas where electricity and refrigeration are spotty at best. Nearly half of the vaccine1 doses around the world are lost to the heat. Also, the cost of refrigeration contributes to about 80 percent of the cost of the vaccines.

 
So silk experts at Tufts University have come up with a potential solution: encase the vaccines in silk protein.
 
Silk proteins contain nanoscale pockets that can hold and protect biological compounds. Inside the silk protein wrap, the compounds stay biologically stable. In the lab, they were able to stabilize4 the measles5, mumps6 and rubella vaccine for more than 6 months at a variety of tropical temperatures.
 
The technology also worked with antibiotics7. Stored at a month at temperatures reaching 140 degrees Fahrenheit8, the antibiotics kept their potency9.  The research is in the Proceedings10 of the National Academy of Sciences. 

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