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英文书摘精选 Why Humans (Not Chimps) Get Cancer为何人类而不是黑猩猩会得癌症?

时间:2018-03-27 07:17:52

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(单词翻译)

You may have heard that humans and chimpanzees have something like 96 percent of our DNA2 in common. So why, then, are diseases like cancer so common in humans but so rare in chimps3? If our DNA is nearly identical, shouldn’t we be at risk for many of the same diseases?
你也许会听说人类和黑猩猩约有96%的DNA相同。那么,为什么人类常常患有比如癌症这样的疾病,而在黑猩猩极少呢?如果我们和猩猩的DNA近乎相同,为何在面对许多相同的疾病时,我们和猩猩的患病率不同呢?

According to one study, the difference is due to something called DNA methylation, which involves the chemical modification4 of DNA. Basically, methylation modifies some DNA positions in the genome, and can also signal cells to switch specific genes5 to the “off” position.
根据一份研究,造成这种差异的原因是一种被称为DNA甲基化的物质,它与DNA的化学变化有关。简单来说,甲基化改变了一些DNA在染色体组中的位置,也可以通知细胞把特殊的基因转换到“关闭”的位置。

Evidently, humans and chimps have different patterns of DNA methylation. So even though we may share many of the same genes, the ways our cells switch these common genes on and off differs. And because at least some of these genes are linked to diseases including cancer, variations in the way DNA methylation happens among humans and chimps may help explain why chimps seem to avoid diseases common in humans.
显然,人类和黑猩猩拥有不同的DNA甲基化模式。因此,尽管人类和猩猩有许多相同基因,但是细胞开关这些相同基因的方式是不同的。而且,因为这些基因中至 少有一部分关系到包括癌症在内的各种疾病,所以人类和猩猩体内DNA甲基化发生的方式不同,或许就能用来解释为什么猩猩能抵御人类常患的疾病。

So what explains the differences among human and chimp1 DNA methylation? It may be partly biological, but scientists also know that environmental factors can affect methylation. So studying methylation in humans and chimps could give scientists clues about how genetics and environment combine to make humans more vulnerable to cancer and other diseases.
那又如何解释人类和猩猩DNA甲基化的不同呢?这或许要牵涉到一部分生物学原理,但是科学家们也认识到环境因素能影响甲基化。因此对人类和猩猩甲基化的研究可能会给于科学家们一些线索,以了解到基因和环境的综合影响是如何使人类更容易患有癌症和其他疾病。


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1 chimp WXGza     
n.黑猩猩
参考例句:
  • In fact,the color of gorilla and chimp are light-color.其实大猩猩和黑猩猩的肤色是较为浅的。
  • The chimp is the champ.猩猩是冠军。
2 DNA 4u3z1l     
(缩)deoxyribonucleic acid 脱氧核糖核酸
参考例句:
  • DNA is stored in the nucleus of a cell.脱氧核糖核酸储存于细胞的细胞核里。
  • Gene mutations are alterations in the DNA code.基因突变是指DNA密码的改变。
3 chimps 2a09048610e52de775e2fe426c063f06     
(非洲)黑猩猩( chimp的名词复数 )
参考例句:
  • Chimps are too scarce, and too nearly human, to be routinely slaughtered for spare parts. 黑猩猩又太少,也太接近于人类,不可以作为人器官备用件说杀就杀。 来自英汉非文学 - 生命科学 - 医学的第四次革命
  • And as nonprimates, they provoke fewer ethical and safety-related concerns than chimps or baboons. 而且作为非灵长类,就不会产生像用黑猩猩或狒狒那样的伦理和安全方面的顾虑。 来自英汉非文学 - 生命科学 - 医学的第四次革命
4 modification tEZxm     
n.修改,改进,缓和,减轻
参考例句:
  • The law,in its present form,is unjust;it needs modification.现行的法律是不公正的,它需要修改。
  • The design requires considerable modification.这个设计需要作大的修改。
5 genes 01914f8eac35d7e14afa065217edd8c0     
n.基因( gene的名词复数 )
参考例句:
  • You have good genes from your parents, so you should live a long time. 你从父母那儿获得优良的基因,所以能够活得很长。 来自《简明英汉词典》
  • Differences will help to reveal the functions of the genes. 它们间的差异将会帮助我们揭开基因多种功能。 来自英汉非文学 - 生命科学 - 生物技术的世纪

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