美国国家公共电台 NPR Seasonal Sniffles? Immunotherapy Tablets Catch On As An Alternative To Allergy Shots

（单词翻译）

RACHEL MARTIN, HOST:

If allergies¹ have you sneezing your way through spring, you are not alone. Allergy² shots are one treatment option, but many allergists are now prescribing some of their patients tablets that can be taken at home. NPR's Allison Aubrey reports.

ALLISON AUBREY, BYLINE³: When I was a kid, I remember weekly treks⁴ to the doctor to get my allergy shot, and thanks to my mom, who made all those trips, the strategy seemed to work. As an adult, I don't have symptoms, and that's because the shots can actually shift or alter your immune system. They're a form of immunotherapy, and the newer tablets, which were approved about five years ago, work in the very same way. Allergist Mike Tankersley who practices in Memphis, Tenn., says that tablets are easy to take.

MIKE TANKERSLEY: It's a little wafer tablet that you put under your tongue. It dissolves in about 10 seconds.

AUBREY: Now, unlike allergy shots, which can be formulated⁵ to treat a whole bunch of allergies with one shot, the tablets target just one allergy. So Tankersley says they're most effective for people who have one or two main allergies that bother them. There are four FDA-approved tablets on the market to treat grass pollens⁷, dust mites⁸ and ragweed.

TANKERSLEY: I've had several patients in my practice who had been very happy with having a product that they can take it home. So those patients who, historically, we didn't really have anything to offer them, is now we've got something to offer those patients.

AUBREY: According to a new survey by the American College of Allergy, Asthma⁹ and Immunology, 73 percent of allergists now prescribed tablets to some of their patients.

TANKERSLEY: There's been a significant change in practice in the United States.

AUBREY: Now, so far there is not a tablet approved for tree pollen⁶ in the U.S., and that's what's really driving all these early spring allergies. But there are tablets for grass pollens, which can start to rise about this time of year and really bother people through the summer. Harold Nelson is an allergist at National Jewish Health in Denver, and he says, in some places, such as the Willamette Valley in Oregon or in Northern California...

HAROLD NELSON: Where grass is way far the predominant allergen, then the grass tablets are great.

AUBREY: Mike Tankersley, the allergist back in Memphis, says most of his patients take allergy shots because they have a lot of allergies, but about 1 in 10 do take the tablets. He says over-the-counter medications, like the nasal steroids and antihistamines¹⁰, work too, but they offer just temporary relief of symptoms. The shots and tablets aim to fix the root cause.

TANKERSLEY: And that's the big advantage of immunotherapy. We're really shooting for a cure.

AUBREY: A way to end or reduce symptoms for the long term. Allison Aubrey, NPR News.