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Study: Repeat COVID Infection Is Riskier1 than First
A new study has found that the risk of death, hospitalization and serious health issues from COVID-19 increases with reinfection regardless of vaccination2.
The study examined U.S. Department of Veterans Affairs data collected from March 1, 2020 through April 6, 2022. It included information on 443,588 patients with one SARS-CoV-2 infection, 40,947 with two or more infections, and 5.3 million who were not infected. Most of the study subjects were male.
"Reinfection with COVID-19 increases the risk of both acute outcomes and long COVID," said Dr. Ziyad Al-Aly of Washington University School of Medicine in St. Louis. He added that this was clear "in unvaccinated, vaccinated3 and boosted people."
Reinfected patients had a doubled risk of death and a tripled risk of hospitalization compared with individuals infected only once. The patients also had increased risks for a number of other health problems, the study, reported in Nature Medicine, found. The problems affected4 the lungs, heart, blood, kidneys, bones and muscles. Reinfection also increased the risk of mental health, brain and nerve disorders5.
"Even if one had prior infection and was vaccinated - meaning they had double immunity6 from prior infection plus vaccines7 - they are still susceptible8 to adverse9 outcomes upon reinfection," said Al-Aly. He was the lead writer of the study.
Susceptible means easily affected or harmed by something.
People with repeat infections were three times more likely to develop lung problems, three times more likely to suffer heart conditions and 60 percent more likely to have brain or nerve disorders, the study found. The risks were highest in the first month after reinfection but were still clear six months later.
The total risks of repeat infection increased with the number of infections, even after examining differences in COVID-19 variants10 such as Delta11, Omicron and BA.5, the researchers said.
"We had started seeing a lot of patients coming to the clinic with an air of invincibility12," Al-Aly told Reuters. "They wondered, 'Does getting a reinfection really matter?' The answer is yes, it absolutely does."
He added that ahead of a season that often involves travel and indoor gatherings13, people should be aware that reinfection is serious and should take steps to avoid getting infected.
Al-Aly explained that researchers are not suggesting serious measures, "but maybe if you're going on a plane, wear a mask." Or, if a person is in a food store, "consider that the person near you may have a weak immune system, and if you wear a mask you might help to protect them," he said.
Words in This Story
acute – adj. very serious or dangerous : requiring serious attention or action
prior – adj. existing or happening before the present time
adverse – adj. bad or unfavorable : not good
invincibility – n. impossible to defeat or overcome
immune – adj. relating to the way your body fights disease
1 riskier | |
冒险的,危险的( risky的比较级 ) | |
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2 vaccination | |
n.接种疫苗,种痘 | |
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3 vaccinated | |
[医]已接种的,种痘的,接种过疫菌的 | |
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4 affected | |
adj.不自然的,假装的 | |
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5 disorders | |
n.混乱( disorder的名词复数 );凌乱;骚乱;(身心、机能)失调 | |
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6 immunity | |
n.优惠;免除;豁免,豁免权 | |
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7 vaccines | |
疫苗,痘苗( vaccine的名词复数 ) | |
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8 susceptible | |
adj.过敏的,敏感的;易动感情的,易受感动的 | |
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9 adverse | |
adj.不利的;有害的;敌对的,不友好的 | |
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10 variants | |
n.变体( variant的名词复数 );变种;变型;(词等的)变体 | |
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11 delta | |
n.(流的)角洲 | |
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12 invincibility | |
n.无敌,绝对不败 | |
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13 gatherings | |
聚集( gathering的名词复数 ); 收集; 采集; 搜集 | |
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