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New Procedure Could Get More TB Patients Treated
An international team of researchers has found that revised protocols2 for diagnosing tuberculosis3 may be more user-friendly for patients and help bring more people into treatment, especially in poorer countries.
In many places around the world where tuberculosis is a major threat, suspected cases are diagnosed by looking through a microscope for the TB bacteria in sputum - the mixture of saliva4 and mucus that the patient coughs up.
Under current protocol1, three specimens5 are collected on two consecutive6 days - one "on-the-spot" in the clinic, one the next morning at home, and then a third "spot" sample when the patient returns to the clinic.
But many patients don't live near a diagnosis7 facility, so often they come once, but don't return for the next day's tests.
Luis Cuevas of the World Health Organization and the University of Liverpool in England and colleagues tested a variation of the protocol, taking two "spot" samples in the clinic an hour apart, and a third one the next day.
"And if you use the new scheme, you end up with exactly the same result. Whether you do it one way or another, you end up with the same number of cases."
Not only that, the results from examining just the first two specimens identified most TB-positive patients. So if both specimens are collected on day one, there is a greater likelihood of an accurate diagnosis.
The studies were done in Ethiopia, Nepal, Nigeria, and Yemen.
Researcher Cuevas says it's important to improve the process of diagnosing tuberculosis. "What we see very frequently is that accessing the diagnosis for TB is often a barrier to access treatment for TB. So, facilitating a rapid diagnosis is very key to improve access to treatment."
There are more high-tech8 diagnostic tests for tuberculosis, but they are as much as 15 times more expensive than microscopic9 examination of the sputum, so in resource-poor countries the less costly10 diagnosis procedure is likely to remain dominant11.
1 protocol | |
n.议定书,草约,会谈记录,外交礼节 | |
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2 protocols | |
n.礼仪( protocol的名词复数 );(外交条约的)草案;(数据传递的)协议;科学实验报告(或计划) | |
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3 tuberculosis | |
n.结核病,肺结核 | |
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4 saliva | |
n.唾液,口水 | |
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5 specimens | |
n.样品( specimen的名词复数 );范例;(化验的)抽样;某种类型的人 | |
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6 consecutive | |
adj.连续的,联贯的,始终一贯的 | |
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7 diagnosis | |
n.诊断,诊断结果,调查分析,判断 | |
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8 high-tech | |
adj.高科技的 | |
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9 microscopic | |
adj.微小的,细微的,极小的,显微的 | |
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10 costly | |
adj.昂贵的,价值高的,豪华的 | |
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11 dominant | |
adj.支配的,统治的;占优势的;显性的;n.主因,要素,主要的人(或物);显性基因 | |
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