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New research suggests ayahuasca, a jungle vine found in the Peruvian rainforest, can have a powerful effect on the human central nervous system when brewed2 with other plants. Researchers say one of ayahuasca's most promising3 uses could be in treating drug and alcohol addiction4.
According to the World Health Organization, medicines derived5 from plants play a major role in the health care of 80 percent of the world's population. Western medicine has synthesized many of these natural drugs, from the painkillers6 in willow7 bark to the anti-cancer compounds in the neem tree, and is constantly searching for more pharmaceuticals9 in the biodiversity of the world's forests.
Ayahuasca is one traditional plant-based medicine that has drawn10 the attention of investigators12. In the South American jungles, it is used in religious ceremonies to induce visions and also as a remedy to cure ills.
Vine of the dead could help improve life
At the Onanyan Shobo spiritual retreat center in the rainforest near Iquitos, Peru, shaman Alfredo Kayruna Canayo shows off a section of the twisting, leafy vine. "What ayahuasca means is vine of the dead," he explains through an interpreter. "Some people call it soul vine."
Ayahuasca is known as a master plant, a very powerful remedy that treats the whole person: body, mind, and soul. "The ayahuasca [can] cure anything you have," the shaman says. "Start with simple things. For example, it's very simple to cure or repel13 the bad energies from your insides. What is the bad energy? One of them could be the fears, then some wound or injury you have."
Shaman Alfredo heads for a treatment at Onanyan Shobo.
Whether the plant is being used for religious or medicinal purposes, ayahuasca is taken only in a ceremonial setting under the direction of an experienced shaman. To turn it into a drink, also called ayahuasca, pieces of the vine are pounded into a pulp14 and combined with several other plants, then brewed down for eight or more hours into a thick orange liquid.
That combination, shaman Alfredo says, is critical. "Only by itself, this plant doesn't work good, you have to add this with the other plant - the chacruna - which is the help to the ayahuasca. In Shipibo culture, they believe the chacruna is the wife of ayahuasca because they help and work together."
A sophisticated chemical concoction15
An international research team is investigating the pharmaceutical8 potential of ayahuasca, known scientifically as Banisteriopsis caapi. Principal investigator11, Dr. Charles Grob, is a professor of psychiatry17 and pediatrics at the UCLA School of Medicine. His team has done a chemical analysis of the medicinal drink.
Pieces of the vine are pounded into a pulp and combined with several other plants, then brewed down for eight or more hours into a thick orange liquid.
While the shaman's characterization of the herbal interaction may be whimsical, Grob says science confirms that the ayahuasca brew1 is a potent16 medication. "It's a very sophisticated form of pharmacology, which somehow the native peoples of the Amazon region have figured out. Ayahuasca is generally a decoction of two plants. Each plant if taken separately has no effects on the human central nervous system, but when taken together there's a very powerful synergy."
The active ingredients in the brew are DMT, a naturally occurring brain chemical similar to serotonin, and a natural antidepressant. DMT is inactivated18 in the human gut19, but when combined with the antidepressant, it can be absorbed by the body.
Grob says one of ayahuasca's most promising uses is in treating drug and alcohol addiction. "Number one, it does not appear to be addictive20 and the individuals do not develop a tolerance21, they do not go through withdrawals22, and generally speaking, it is very unusual for people to take it on consecutive23 days over an extended period of time."
The potion also has anti-parasitic properties, which can help prevent malaria24. There is also some evidence that it diminishes the symptoms of Parkinson's disease.
An illegal brew, for now
The U.S. Food and Drug Administration classifies the principal active ingredient in ayahuasca as a Schedule 1 controlled substance, which is not considered to have any legitimate25 medical use. As a result, the ayahuasca brew is illegal in the United States, and most of the pharmaceutical studies are being conducted in South America.
Grob says the studies are important. "There's great potential to learn about the range of ayahuasca and to explore its therapeutic26 value, but first steps first, and I think first we need to fully27 understand how it's utilized28 in South America and then do trials in the U.S. and Europe."
Retreats like Onanynan Shobo in the Peruvian jungle, have become popular destinations for the medical tourism industry.
Because many Shamans claim ayahuasca cures a variety of cancers, tumors, and other diseases, the Peruvian jungle has become a popular destination for the medical tourism industry.
Most of the visitors at Onanynan Shobo, where Shaman Alfredo practices, are European, with the remainder coming from the United States, Australia and Asia.
As long as its use in western medicine is illegal, anyone wishing to explore ayahuasca's medical benefits will have to come to the source in South America.
1 brew | |
v.酿造,调制 | |
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2 brewed | |
调制( brew的过去式和过去分词 ); 酝酿; 沏(茶); 煮(咖啡) | |
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3 promising | |
adj.有希望的,有前途的 | |
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4 addiction | |
n.上瘾入迷,嗜好 | |
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5 derived | |
vi.起源;由来;衍生;导出v.得到( derive的过去式和过去分词 );(从…中)得到获得;源于;(从…中)提取 | |
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6 painkillers | |
n.止痛药( painkiller的名词复数 ) | |
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7 willow | |
n.柳树 | |
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8 pharmaceutical | |
adj.药学的,药物的;药用的,药剂师的 | |
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9 pharmaceuticals | |
n.医药品;药物( pharmaceutical的名词复数 ) | |
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10 drawn | |
v.拖,拉,拔出;adj.憔悴的,紧张的 | |
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11 investigator | |
n.研究者,调查者,审查者 | |
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12 investigators | |
n.调查者,审查者( investigator的名词复数 ) | |
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13 repel | |
v.击退,抵制,拒绝,排斥 | |
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14 pulp | |
n.果肉,纸浆;v.化成纸浆,除去...果肉,制成纸浆 | |
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15 concoction | |
n.调配(物);谎言 | |
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16 potent | |
adj.强有力的,有权势的;有效力的 | |
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17 psychiatry | |
n.精神病学,精神病疗法 | |
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18 inactivated | |
v.使不活泼,阻止活动( inactivate的过去式和过去分词 ) | |
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19 gut | |
n.[pl.]胆量;内脏;adj.本能的;vt.取出内脏 | |
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20 addictive | |
adj.(吸毒等)使成瘾的,成为习惯的 | |
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21 tolerance | |
n.宽容;容忍,忍受;耐药力;公差 | |
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22 withdrawals | |
n.收回,取回,撤回( withdrawal的名词复数 );撤退,撤走;收回[取回,撤回,撤退,撤走]的实例;推出(组织),提走(存款),戒除毒瘾,对说过的话收回,孤僻 | |
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23 consecutive | |
adj.连续的,联贯的,始终一贯的 | |
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24 malaria | |
n.疟疾 | |
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25 legitimate | |
adj.合法的,合理的,合乎逻辑的;v.使合法 | |
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26 therapeutic | |
adj.治疗的,起治疗作用的;对身心健康有益的 | |
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27 fully | |
adv.完全地,全部地,彻底地;充分地 | |
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28 utilized | |
v.利用,使用( utilize的过去式和过去分词 ) | |
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