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FDA considers a Pfizer booster and a Moderna vaccine for children

时间:2023-05-26 08:07:31

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FDA considers a Pfizer booster and a Moderna vaccine1 for children

Transcript2

Pfizer has asked for authorization3 for the first booster for children 5 to 11 and Moderna is poised4 to ask for authorization for the first vaccine for children younger than 5.

RACHEL MARTIN, HOST:

We are beginning this hour with new developments on the effort to protect kids from COVID. Pfizer and BioNTech just asked the Food and Drug Administration to authorize5 the first booster shot for children ages 5 to 11. And any day now, Moderna is expected to seek authorization for the first vaccine for children younger than 5. NPR health correspondent Rob Stein joins us this morning. Hi, Rob.

ROB STEIN, BYLINE6: Good morning, Rachel.

MARTIN: Before we get to the vaccine news, let's start with some new data out from the CDC about how many people, including kids, have been infected with COVID. What's the latest?

STEIN: You know, Rachel, does it feel like almost everyone you know has gotten COVID-19 by now? Well, you know...

MARTIN: A lot, yeah.

STEIN: Yeah, there's a good reason for that. The CDC data says that the omicron variant7 spread so fast this winter that almost 60% of everyone in the U.S. has antibodies to the virus. And that number is even higher for children - almost 75% of kids ages 11 and younger. That means lots of people have at least some immunity8 at this point and helps explain why the U.S. hasn't experienced yet another big surge yet.

MARTIN: OK. So 75% of kids have antibodies.

STEIN: Right.

MARTIN: That's what you said?

STEIN: Yep.

MARTIN: Does that mean these kids still need vaccinations10 or boosters?

STEIN: You know, the CDC says yes, absolutely. First of all, you know, one-quarter of kids still don't have any immunity. And the CDC says vaccination9 provides even stronger, perhaps broader, protection for those who have already gotten infected. So the - you know, the CDC is actually frustrated11 that most parents still haven't vaccinated12 or boosted their kids.

MARTIN: So we know kids ages 12 and older are already eligible13 for booster shots. Now Pfizer and BioNTech want the FDA to OK a booster for younger kids, too, right?

STEIN: Yeah, yeah. The companies say a third shot six months after the second shot can safely pump up antibodies for kids ages 5 to 11, especially antibodies that can fight off the omicron variant.

Now, Rachel, there's a bit of mixed opinion among independent experts about whether kids ages 5 to 11 need a booster yet. Some say, look, protection from two shots clearly weakens as the months go by, especially against omicron. And while kids don't tend to get as sick as adults, COVID can still pose a danger to kids. So we should do everything possible to protect them, especially now that no one's wearing masks and the numbers are creeping up again.

But others argue two shots are still keeping kids from getting seriously ill. And the evidence boosters are definitely needed just isn't there yet. So the FDA will have to decide who's right.

MARTIN: Meanwhile, really young kids still have not been able to get even their first shots.

STEIN: Right.

MARTIN: Moderna is expected to ask the FDA to authorize a vaccine for children younger than 5 this week finally. I mean, is this going to happen?

STEIN: You know, Moderna says its low-dose pediatric vaccine looks safe and can boost antibodies to levels equivalent to the adult vaccine for kids as young as 6 months old. That said, the protection still doesn't look that great against omicron. So that's raised questions about whether three doses are really needed. That's what happened with the Pfizer-BioNTech pediatric vaccine, and the FDA is waiting to see if three shots of that vaccine work better.

So while everyone's hoping to get a vaccine for these kids by this month, it now looks like the FDA's probably not going to take this up until June. And that's obviously not good news to all those parents of very young kids who are frustrated and angry that it's already taken this long to get a vaccine for their kids.

MARTIN: NPR health correspondent Rob Stein, thank you.

STEIN: Sure thing, Rachel.


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1 vaccine Ki1wv     
n.牛痘苗,疫苗;adj.牛痘的,疫苗的
参考例句:
  • The polio vaccine has saved millions of lives.脊髓灰质炎疫苗挽救了数以百万计的生命。
  • She takes a vaccine against influenza every fall.她每年秋季接种流感疫苗。
2 transcript JgpzUp     
n.抄本,誊本,副本,肄业证书
参考例句:
  • A transcript of the tapes was presented as evidence in court.一份录音带的文字本作为证据被呈交法庭。
  • They wouldn't let me have a transcript of the interview.他们拒绝给我一份采访的文字整理稿。
3 authorization wOxyV     
n.授权,委任状
参考例句:
  • Anglers are required to obtain prior authorization from the park keeper.垂钓者必须事先得到公园管理者的许可。
  • You cannot take a day off without authorization.未经批准你不得休假。
4 poised SlhzBU     
a.摆好姿势不动的
参考例句:
  • The hawk poised in mid-air ready to swoop. 老鹰在半空中盘旋,准备俯冲。
  • Tina was tense, her hand poised over the telephone. 蒂娜心情紧张,手悬在电话机上。
5 authorize CO1yV     
v.授权,委任;批准,认可
参考例句:
  • He said that he needed to get his supervisor to authorize my refund.他说必须让主管人员批准我的退款。
  • Only the President could authorize the use of the atomic bomb.只有总统才能授权使用原子弹。
6 byline sSXyQ     
n.署名;v.署名
参考例句:
  • His byline was absent as well.他的署名也不见了。
  • We wish to thank the author of this article which carries no byline.我们要感谢这篇文章的那位没有署名的作者。
7 variant GfuzRt     
adj.不同的,变异的;n.变体,异体
参考例句:
  • We give professional suggestions according to variant tanning stages for each customer.我们针对每位顾客不同的日晒阶段,提供强度适合的晒黑建议。
  • In a variant of this approach,the tests are data- driven.这个方法的一个变种,是数据驱动的测试。
8 immunity dygyQ     
n.优惠;免除;豁免,豁免权
参考例句:
  • The law gives public schools immunity from taxation.法律免除公立学校的纳税义务。
  • He claims diplomatic immunity to avoid being arrested.他要求外交豁免以便避免被捕。
9 vaccination bKGzM     
n.接种疫苗,种痘
参考例句:
  • Vaccination is a preventive against smallpox.种痘是预防天花的方法。
  • Doctors suggest getting a tetanus vaccination every ten years.医生建议每十年注射一次破伤风疫苗。
10 vaccinations ed61d339e2970fa63aee4b5ce757cc44     
n.种痘,接种( vaccination的名词复数 );牛痘疤
参考例句:
  • Vaccinations ensure one against diseases. 接种疫苗可以预防疾病。 来自《简明英汉词典》
  • I read some publicity about vaccinations while waiting my turn at the doctor's. 在医生那儿候诊时,我读了一些关于接种疫苗的宣传。 来自《简明英汉词典》
11 frustrated ksWz5t     
adj.挫败的,失意的,泄气的v.使不成功( frustrate的过去式和过去分词 );挫败;使受挫折;令人沮丧
参考例句:
  • It's very easy to get frustrated in this job. 这个工作很容易令人懊恼。
  • The bad weather frustrated all our hopes of going out. 恶劣的天气破坏了我们出行的愿望。 来自《简明英汉词典》
12 vaccinated 8f16717462e6e6db3389d0f736409983     
[医]已接种的,种痘的,接种过疫菌的
参考例句:
  • I was vaccinated against tetanus. 我接种了破伤风疫苗。
  • Were you vaccinated against smallpox as a child? 你小时候打过天花疫苗吗?
13 eligible Cq6xL     
adj.有条件被选中的;(尤指婚姻等)合适(意)的
参考例句:
  • He is an eligible young man.他是一个合格的年轻人。
  • Helen married an eligible bachelor.海伦嫁给了一个中意的单身汉。

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